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Coulpling Reagents

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Coupling reagents have been applied widely in the synthesis of polypeptides, nucleosides and carbohydrates for the benefits of rate-enhancement of the reaction in high yields under mild reaction conditions with less despumated by-product and following the principle of "atomic economy".

J&K provides various coupling reagents on the bases of molecular structures classified as carbodiimide, phosphorus, urea, etc. The phosphorus cations and urea cations perform the best.

Reference D. Gomez, R. Paterski, T.lt Lemarteleur, S.Y. Kazuo, J.L. Mergny, J.F. Riou, J. Biochemistry. 2004, 279, 41487-41494.

Carbodiimides

structure Product no. description cas pricing
275928 N,N'-Dicyclohexylcarbodiimide, 99% 538-75-0 Pricing
134385 N,N'-Diisopropylcarbodiimide, 99% 693-13-0 Pricing
495017 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide, 97% 1892-57-5 Pricing
211112 N-(3-Dimethylaminopropyl)-N'-ethylcarbodiimide hydrochloride, 99% 25952-53-8 Pricing
284163 N-(3-Dimethylaminopropyl)-N'-ethylcarbodiimide methiodide, 98% 22572-40-3 Pricing

Carbonylimidazole Derivatives

structure Product no. description cas pricing
180331 N,N'-carbonyldiimidazole, 98% 530-62-1 Pricing
579542 1,1'-Carbonyl-di-(1,2,4-triazole), 97% 41864-22-6 Pricing
130035 4,5-Dicyanoimidazole, 99% 1122-28-7 Pricing

Phosphoniums

structure Product no. description cas pricing
151585 Benzotriazol-1-yloxytris(dimethylamino)-phosphonium hexafluorophosphate, 98% 56602-33-6 Pricing
154189 Benzotriazol-1-yloxytrispyrrolidinophosphonium hexafluorophosphate, 99% 128625-52-5 Pricing
241290 Bromo-tris-pyrrolidino-phosphonium hexafluorophosphate, 97% 132705-51-2 Pricing

Uroniums

structure Product no. description cas pricing
249763 O-(7-Azabenzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate, 99% 148893-10-1 Pricing
172711 O-(Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate, 97% 125700-67-6 Pricing
296131 O-(1H-6-Chlorobenzotriazol-1-yl)-1,1,3,3-tetramethyluronium hexafluorophosphate, 98% 330645-87-9 Pricing
405354 O-(1,2-Dihydro-2-oxo-pyridyl)-1,1,3,3-tetramethyluronium tetrafluoroborate, 99% 125700-71-2 Pricing
435747 O-[(Ethoxycarbonyl)cyanomethylenamino]-N,N,N',N'-tetramethyluroniumtetrafluoroborate, 98% 136849-72-4 Pricing
253208 O-(5-Norbornene-2,3-dicarboximido)-N,N,N’,N’-tetramethyluronium tetrafluoroborate, 98% 125700-73-4 Pricing
511438 N,N,N',N'-Tetramethyl-O-(N-succinimidyl)uronium tetrafluoroborate, 97% 105832-38-0 Pricing

Active Esters

structure Product no. description cas pricing
278823 4-Nitrophenyl chloroformate, 98% 7693-46-1 Pricing
191243 N,N'-Disuccinimidyl carbonate, 99% 74124-79-1 Pricing
526321 N,N'-Disuccinimidyl carbonate, 99% 74124-79-1 Pricing
541810 4-Nitrobenzyl chloroformate, 97% 4457-32-3 Pricing
186836 N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline, 98% 16357-59-8 Pricing

Others

structure Product no. description cas pricing
195731 Bis(2-oxo-3-oxazolidinyl)phosphinic chloride, 97% 68641-49-6 Pricing
273795 6-Chloro-1-hydroxybenzotriazol, 98% 26198-19-6 Pricing
199766 N,O-Dimethylhydroxylamine hydrochloride, 99% 6638-79-5 Pricing
183144 N-Hydroxysulfosuccinimide sodium salt, 98% 106627-54-7 Pricing
303005 1-Hydroxy-7-azabenzotriazole, 99% 39968-33-7 Pricing
110209 N-Hydroxyphthalimide, 98% 524-38-9 Pricing
117997 N-Hydroxysuccinimide, 98% 6066-82-6 Pricing
145125 Pentafluorophenol, 99% 771-61-9 Pricing
244874 Trifluoromethanesulfonic anhydride, 98% 358-23-6 Pricing