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Lewis Acid

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As electron pair acceptors, Lewis acids (LAs) are widely used in organic synthesis. As catalysts, Lewis acids have been successfully used in Mannich reactions, Friedel-Crafts reactions, re-arrangement reactions, synthesis of α-amino acids, formation of quinoline rings, ester exchange reactions and Diels-Alder reactions.

J. Am. Chem. Soc., 2011, 133 (5), 1248–1250.

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